- March 24, 2018
- Posted by: Dr. Nnamdi Elenwoke
- Category: Health
At a glance…
Each year, more than 100 million animals – mice, rats, frogs, dogs, cats, rabbits, hamsters, guinea pigs, monkeys, fish and birds – die in US laboratories for biology, medical training, curiosity experimentation and chemical, pharmaceutical, food and cosmetic tests. Before dying, some are forced to inhale toxic gases, others are immobilized with restrictions for hours, some have holes in the skull and others have burned skin or crushed spinal cord.
Many companies have realized that there are more humane ways to make good products without relying on animal testing. There are valid alternatives to use our furry friends; the other options were even more reliable and less expensive. Some of the possibilities are: chemical assays, tissue culture systems, cell and organ cultures, cloned human skin cells, human skin patches or computer/mathematical models.
The real trick is that animal tests are not even practical. Studies have shown that 92% of experimental drugs that are safe and effective in animals fail in clinical trials in humans, or simply do not work. According to the former Scientific Director of Huntingdon Life Sciences, animal tests and human results coincide only 5-25% of the time. With hundreds of other viable techniques, cell culture toxicology methods yield precision rates of 80-85%. In addition, 75% of side effects that occur in animals do not apply to humans. In contrast, half of the side effects identified in humans can not be detected in laboratory animals.
Obviously, experimentation with animals is a useless parody that must be stopped. The animals do not belong to us. The animals are not killing us. The animals are not free from these tests. Animals are not born to be tested in a laboratory. It is our duty as decent human beings to fight until the abuse is over.
It is not surprising that promising treatments in animals rarely work in humans. Not only time, money and animal life are wasted (with much suffering), but effective treatments are mistakenly eliminated and harmful treatments are passed. Support for animal testing is largely based on anecdotes and, in our opinion, is not supported by available scientific evidence.
Despite many decades of study of diseases such as cancer, Alzheimer’s disease, Parkinson’s disease, diabetes, stroke and AIDS in animals, we still have no reliable remedies.
Advantages of animal experimentation
- Contributes to many treatments that save many lives
Most of the medical advances that have occurred in the past 100 years were direct results of animal research and experimentation, according to the California Association of Biomedical Research. Insulin, for example, was discovered during an experiment in which the dog’s pancreas was removed.
- Provides adequate life, test subject of the whole body system
No other living being on this planet has the anatomical structure closest to humans.
- Humans and animals are almost identical in many ways
Chimpanzee DNA is 99% similar in humans, while mouse genetics are similar to 98%. Humans and animals are also biologically similar, with the same set of organs, blood circulation and central nervous system, so they are affected by the same disease and the same health conditions.
- Provide an ethical alternative for testing
Most people would say that it is unethical to use human for invasive experimental procedures, especially when it can lead to death. The lives of human volunteers should not be put at risk when testing drugs for side effects or potential toxicity.
- Offer benefits to the animals themselves
Experimentation with animals is not only beneficial for humans but also for animals. If the vaccines have not been tested on them, many of them could have died of rabies, the infectious hepatitis virus, anthrax, feline leukemia and canine parvovirus. The remedies for hip dysplasia and glaucoma have also been discovered through animal testing.
Disadvantages of animal experimentation
- Cruel and inhumane treatment
Test protocols in animals are often painful for the subjects evaluated. They are immobilized physically for long periods, causing burns, wounds and pain to test the effects and remedies of the healing process, and even killed by deformation of the neck or force-fed, deprived of food and water, suffocation.
- Animals are poor test subjects
This statement is in direct contradiction to what proponents believe the anatomical and biological similarity between animals and humans, due to the many metabolic, cellular and anatomical differences between the two species. The use of rats for toxicity, for example, should not be considered reliable since humans are far from rats at 70 kilograms according to Thomas Hartung, a de facto toxicology professor at Johns Hopkins University.
- The success of animal testing is not synonymous with human safety
When sleeping pill thalidomide was tested on pregnant rats, mice, cats and guinea pigs, there has been no incidence of birth defects, except when administered in extremely high doses. However, when pregnant women used it, it produced severe malformations that affected 10,000 babies.
- It can lead to a deceptive investigation
Some drugs and products that are harmful to animals are really valuable to humans. Aspirin, for example, is almost shown because it turned out to be dangerous for animals.
- There are less expensive alternatives for animal experimentation
Despite what proponents insist, cell cultures in a Petri dish or in vitro (in glass) are not really useless or insufficient. They may even produce more relevant results than tests on animals.
Experiments that require the use of animals
- Meat Animal Research Center
As a result of reports of horrific cruelty at the Animal Meat Research Center (MARC), funded by the United States, including animals that suffered, died of starvation and died.
- Experiments with monkeys
Each year, more than 100,000 monkeys are experienced in the United States. Monkeys in laboratories are subject to painful, invasive and irrelevant experiments. They are hungry and trapped, and they are infected with diseases and pumped full of chemicals and drugs. Experimenters drill holes and screw objects in their heads. Finally, the animals are killed.
- Sexual experiments
Currently, the NIH is funding dozens of horrific studies on sexual behavior in which animals have the sexual pleasure zone of their damaged brains and mutilated genitalia. Mice and rats similar to the ones shown below have all the cut skin of their penises. Your genitals are stimulated electrically with electrodes and injected with chemicals. Then they are killed, and their penises are dissected.
- Military tests
Each year, more than 10,000 live animals are killed, stabbed, mutilated and killed in cruel military training exercises.
- Experiments of smoking
Health officials have known for decades that cigarette smoking causes diseases and that animal tests are a poor indicator of these effects. However, tobacco companies continue to force animals to smoke, although there are more effective alternatives. Two of the world’s largest cigarettes continue to perform painful, archaic and irrelevant tobacco tests on animals, although they are not required by law and higher test methods without animals are readily available.
Future of Animals in Medical Sciences
- The functional fabric can be done from spinach
In an experiment in 2017, researchers at the Worcester Polytechnic Institute (WPI) converted a spinach leaf into functional tissue of the heart. Like the fragile network of blood vessels whose human heart cannot function without it, plants also have a delicate vascular system, which until now has not been successful in attempts to synthesize through 3D printing.
Since spinach is easy to grow, inexpensive and requires only a fraction of the resources, compared to the resources used to raise animals, the future of the relationship between animals and science can deteriorate with the rise of the fabrics of spinach.
- Human beings con consent for controlled tests
Human beings legally authorized to make their own decisions can give or reject consent at will, and withdraw consent at any time for medical examinations. Whether it is a test that involves eating plants to measure cholesterol reduction or administering tissue, there is still a wide range of invasive and non-invasive tests that contribute to medical research, which require a consenting human. On the other hand, animals (despite sensitivity) cannot give verbal or non-verbal consent, nor understand what is being done to them, nor why. What they can do, however, is feel pain.
- The simulation of the computer can advance the biological understanding
Computers can now simulate bodies accurately and perform 3D digital experiments. Experiments with live animals are costly, slow, risky and often impractical. Fortunately, the technological advances and the greater depth of biological understanding offered by this alternative animal research are enormous.
With magnetic resonance imaging (MRI) and ultrasound already implemented and in practice extended, the medical industry is well aware of how computer technology provides meaningful data that is unique to each patient. Many believe it is imminent that technology will prevail over animals in science.
- Human cells can be studied “In Vitro”
Like “clean meat,” which is obtained by extracting animal stem cells from an animal and then growing them in a laboratory, human stem cells can also be extracted, studied and used effectively. The cells can be studied in cultures for the development of drugs, therapeutic proteins and drug filters. NAVS said: “Cultured cells are easier to manipulate molecularly, faster, cheaper and more reproducible than animal models.” It is important to note that human cells can be studied in vitro and offer the possibility of reducing the use of animals in several areas of study. “
Specifically, induced pluripotent stem cells (iPSCs) are extracted from patients with a disease of interest, which can then be reprogrammed and manipulated; to study the cellular reaction. IPSCs are already used to develop model medicines and diseases, which is an important element of personalized medicine.